The most amazing fact about the Mother Nature is that it has provided us with reasons for birth and reason for death of all its creations, and by way of this it maintains balance. Through advancing life, mankind is encountered with various challenging situations and every time Nature provides us with a clue towards life. As we interact more with nature with our knowledge, we are striving more towards life and its challenges. Alzheimer’s disease (AD) is one of most challenging neurodegenerative disorders and we are exploring the clue to encounter this through Nature itself.